Orangeburg’s most charming boutique inn is nestled in the heart of historic downtown Orangeburg, SC and along the SC National Heritage Corridor Trail, Thee Matriarch satisfies the need for a full service small to medium size venue featuring elegantly themed guest quarters and meeting rooms. Elegantly strong and tenaciously beautiful, Thee Matriarch Bed & Breakfast, Meeting and Special Events Venue exemplifies all of the fine attributes required to justify its name. Each room at Thee Matriarch is named to honor some of those outstanding women.