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Ste. Genevieve Vacation Rental

Main Street Inn B&B

Professional Bed and Breakfast hosted by Main Street Inn B&B

About The Property

Originally built in 1882, as the Meyer Hotel, the Main Street Inn B&B has long been considered one of Missouri’s finest bed and breakfast establishments. Having undergone and completed an extensive renovation and reopening in 2017, the Main Street Inn B&B’s proprietors, Susan O’Donnell and Patrick Fahey would like to welcome you to what we hope will be a truly wonderful, relaxing and memorable experience. The Main Street Inn B&B has ten rooms, each with a distinctive design, private baths, eco-friendly toiletries, hair dryers, irons, fine line


Accepts Gift Cards

Ste. Genevieve, Missouri 63670

Location provided after the reservation is made.